Sestrin2 Expression Has Regulatory Properties and Prognostic Value in Lung Cancer
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چکیده
منابع مشابه
Thrombocytosis has a negative prognostic value in lung cancer.
BACKGROUND Solid tumours have worse prognosis when associated with thrombocytosis. Our study assessed the prognostic value of thrombocytosis, and its relation with smoking habits in lung cancer. PATIENTS AND METHODS A total of 398 patients were operated on then divided into two groups, those with normal platelet counts (n=312), and those with thrombocytosis (n=86); 348 out of 398 patients had...
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Background: Numerous studies confirmed that significant decrease in tissue decorin (DCN) expression is associated to tumor progression and metastasis in certain types of cancer including prostate cancer (PC). However, the potential prognostic value of tissue DCN in PC has not yet been investigated. Methods: A total number of 40 PC and 42 patients with benign prostatic hyperplasia (BPH) were inv...
متن کاملEvaluation of the Prognostic Value and TRIP13 gene Expression in Gastric Cancer
Introduction: Gastric cancer is a major public health issue worldwide. The factors that initiate cancer are not well understood, however aberrant expression of genes is associated with this cancer. TRIP13 plays pivotal roles in meiotic recombination, DNA repair, and cell cycle progression. An increasing body of evidence suggests that TRIP13 may possess functions other than meiosis and mitosis, ...
متن کاملMicroRNA-155 expression has prognostic value in patients with non-small cell lung cancer and digestive system carcinomas.
OBJECTIVE Published data have shown that microRNAs (miRNAs) could play a potential role as diagnostic and prognostic indicators in cancers. Data for the predictive value of microRNA-155 are inconclusive. The aim of the present analysis was therefore to evaluate the role of miR-155 in prognosis for patients with a variety of carcinomas. METHODS Relevant studies were identified by searching Pub...
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BACKGROUND Oxidative stress and redox-regulating enzymes may potentially accelerate pancreatic carcinogenesis and also affect chemoresistance. Recently major antioxidant response regulator NF-E2-related factor 2 (Nrf2) has been linked to poor prognosis in pancreatic cancer. Nrf2 activity is strictly regulated by oxidative stress sensor Kelch-like ECH-associated protein 1 (Keap1). Oxidative DNA ...
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ژورنال
عنوان ژورنال: Journal of Personalized Medicine
سال: 2020
ISSN: 2075-4426
DOI: 10.3390/jpm10030109